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| SODIUM HYALURONATE | ||
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PRODUCT IDENTIFICATION |
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| CAS NO. | 9067-32-7 |
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| EINECS NO. | 232-678-0 | |
| FORMULA | (C14H20NO11Na)n | |
| MOL WT. | 800,000 - 1,600,000 | |
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H.S. CODE |
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TOXICITY |
Oral rat LD50: 800mg/kg |
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| SYNONYMS | Hyalgan; | |
| Hyaluronic acid, sodium salt; Healon; Hyalurone sodium; | ||
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CLASSIFICATION |
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PHYSICAL AND CHEMICAL PROPERTIES |
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| PHYSICAL STATE | White powder | |
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| SPECIFIC GRAVITY | soluble | |
| SOLUBILITY IN WATER | ||
| pH | 5.0 - 8.5 | |
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AUTOIGNITION |
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NFPA RATINGS |
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REFRACTIVE INDEX |
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| FLASH POINT |
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| STABILITY | Stable under ordinary condiions | |
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APPLICATIONS |
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| Hyaluronic acid, a kind of mucopolysaccharides (also known as glycosaminoglycans), is an integral part of the gellike substance found in animal connective tissue, synovial fluid of joints and the vitreous humor of the eyes. It contains amino-sugar unit and uronic acid. It has the physiological function of absorbing and retaining water to form jelly matrix for the maintaining cell structure and protecting cell against bacterial infections. Commercially, various HA products are available for ophthalmology, arthritis and odontology. They are widely used in cosmetics and dermatologists for antiaging and moisturizing. | ||
| SALES SPECIFICATION | ||
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SOLID |
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APPEARANCE |
White solid | |
| CONTENT |
85.0%
min
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| NITROGEN | 2.8 - 4.0% | |
| GLUCURONIC ACID | 40.0 ± 3.0% | |
| ARSENIC | 2ppm | |
| HEAVY METALS | 20ppm | |
| LOSS ON DRYING | 15.0% max | |
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INJECTION |
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DESCTIPTION |
Sodium hyaluronate for ophthalmic surgery, pre-filled syringe | |
| COMPOSITION | 10mg/ml | |
| INJECTION VOLUME | -
Cataract: 0.2~04 ml - Glaucoma: 0.3~0.5 ml - Keratotransplantation: 0.2~0.6 ml - Trauma: 0.1~0.6 ml |
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UNIT SIZE |
0.4ml, 0.55ml, 0.6ml, 0.85ml, 1.0ml in pre-filled syringe/pack | |
| STORAGE CONDITION | light-resistant hermetic container at 2 C in the refrigerator | |
| SHELF LIFE |
36months |
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| TRANSPORTATION | ||
| PACKING | ||
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| OTHER INFORMATION | ||
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